Similarly, we have summarized the signaling pathways associated with abnormal lipid metabolism in tumor cells, such as NF‐κB, STAT3, Hippo, Wnt/β‐catenin, and Notch signaling pathways, which can all alter different aspects of lipid metabolism in tumor cells and increase lipid synthesis in tumor cells, thereby promoting tumor progression. Here, NFKB1 is linked to neoplasm.