However, consistent with most previous findings of a more significant increase in blood GFAP in Alzheimer’s disease patients than in FTLD patients,12,13,38-40 the plasma GFAP level was 2-fold higher in the Alzheimer’s disease group than in the FTLD group and effectively distinguished these two patient groups (AUC 0.894) in this study. This evidence concerns the gene GFAP and Alzheimer disease.