VEGFD and systemic sclerosis: To investigate whether BM-MSC-CM and WJ-MSC-CM act as a positive modulator of angiogenesis in SSc fibroblasts, we treated the cells with BM-MSC-CM and WJ-MSC-CM for 24 h and measured the mRNA expression levels of several proangiogenic mediators (VEGF-A, VEGF-B, VEGF-C, VEGF-D).