GPIHBP1 and familial chylomicronemia syndrome: Familial chylomicronemia syndrome (FCS) identifies persistent chylomicronemia that is caused by a biallelic combination of pathogenic variants in the lipoprotein lipase (LPL) gene or in genes necessary to its function specifically lipase maturation factor 1, glycosylphosphatidylinositol anchored high-density lipoprotein binding protein 1 (GPIHBP1), apolipoprotein(APO)-C2 or -A5, involved in LPL maturation, anchoring to the endothelial wall or binding to chylomicrons, and very low density lipoprotein (VLDL) [4, 5].