We calculated the risk scores for BC patients in TCGA-BRCA to evaluate survival risk using the following formula: risk score= (-0.393) × ADPGK + (-0.387) × HNRNPA1 + (-0.209) × PGAM1 + (-0.196) × PIM2 + (-0.145) × YWHAZ + 0.186 × PTK2 + 0.286 × VDAC1 + 0.391 × CS + 0.545 × PGK1 + 1.43 × GAPDHS. The gene discussed is GAPDHS; the disease is breast cancer.