The role of GPR132 in lactate is less well understood, but studies have shown that GPR132 is expressed in the human epidermis, keratinocytes, fibroblasts, melanocytes, and various skin tumors, such as malignant melanoma, compound nevus cell nevi, and basal cell carcinoma (51, 55, 56). This evidence concerns the gene GPR132 and basal cell carcinoma.