Aiming for investigation the protein patterns of UBA1/6 in various tumors, the UALCAN database was used in this study to detect their protein level, and the results suggested that UBA6 was highly expressed in most cancers, while the protein expression of UBA1 was lower in renal cell cancer, lung cancer and glioblastoma than corresponding normal samples (Figures 2A, B). Here, UBA1 is linked to lung cancer.