However, there were some significant peculiarities in 18 cancers, where UBA6 expression was significantly increased in both HNSC and KICH (P<0.001) and not different in UBA1 (P>0.05) when compared with normal tissues, while the opposite was true in PRAD and THCA, where UBA1 expression was significantly increased in both (P<0.001), while in UBA6 there was no difference (P>0.05). This evidence concerns the gene UBA1 and cancer.