Functional enrichment, GO annotation and KEGG assessment uncovered that the CMTM3, MYO16, STAT1, STAT2, chi-let-7b-3p, chi- miR-671-5p, chi-miR-451-5p, chi-miR-149-5p, chi-miR-145-5p, circCOL1A1, circACTN1, circITGA6, and circCOBLL1 could participate in regulating YRDWG gHFSCs growth and HF development. The gene discussed is STAT2; the disease is hydrops fetalis.