LEP and Anorexia: The new findings are as follows: (1) plasma NPY and leptin were elevated and plasma acyl-ghrelin tended to decrease in the early phase of the chemotherapy session; (2) plasma motilin increased significantly on days 5 and 8 compared to baseline only in the CINV group, and the levels were significantly higher in the CINV group than in the non-CINV group; (3) plasma leptin remained significantly higher on day 5 compared to baseline only in the anorexia group.