Recently, Zulong found visceral adipose tissue‐derived exosomes in high‐fat diet‐fed obese mice promoted macrophage foam cell formation and M1 macrophage transition, decreased macrophage‐regulated cholesterol efflux via downregulation of ABCA1 and ABCG1, and further exacerbated atherosclerosis [89]. Here, ABCG1 is linked to atherosclerosis.