Univariate analysis showed that age, years since menopause, the prevalence of diabetes and the levels of β-CTX, P1NP, TC, LDL, GLU, UA, FSH, and LH were risk factors and BMI, 25-(OH)-D, phosphate, E2, and T were protective factors for bone loss in the studied women (Table 2). Here, PLOD1 is linked to diabetes mellitus.