In the literature [8–13, 15–18] (Table 1, Table S4), the ARID2 associated phenotype mainly consists of psychomotor delay (96%), hypotonia (70%), speech disorders (87%), behavior problems (65%), variable range of ID from mild to severe (96%), ectodermal features (hair 50%, and nail anomalies 38%), and few dental anomalies (24%). The gene discussed is ARID2; the disease is speech disorder.