CHD8 and Delayed speech and language development: ARID2 had the highest percent of DMPs overlapping with Intellectual developmental disorder with seizures and language delay (IDDSELD) (29%, SETD1B), BAFopathy (28%, including ARID1A, ARID1B, SMARCB1, SMARCA2, SMARCA4), CHARGE (24%, CHD7), Intellectual developmental disorder with autism and macrocephaly (IDDAM) (23%, CHD8), Kabuki syndrome (22%, KMT2D), Intellectual developmental disorder, X-linked 93 (MRX93) (22%, BRWD3) and Intellectual developmental disorder, X-linked 97 (MRX97) (22%, ZNF711) (Figs. 4B and  S5).