SRD5A2 and Familial prostate cancer: In the coding region, different genetic and molecular reports have shown that 2 well-known SRD5A2 gene polymorphisms or nsSNVs (rs9282858: c.145G>A, p.A49T; rs523349: c.265C>G, p.L89V; accessed on March 2, 2023) might be related to benign prostatic hyperplasia and possibly prostate cancer [15–18].