We next ran RCSP on 137 samples collected from CD4+ T cells of multiple sclerosis (MS; GSE137143) as well as Perturb-seq data of 1,989,578 K562 cells, which can be genetically engineered into artificial antigen-presenting cells for expanding T cells (Butler and Hirano, 2014; Replogle et al., 2022). Here, CD4 is linked to multiple sclerosis.