Compared with those in the S group, the numbers of both NK and DC cells, which are involved in innate immunity, tended to increase following ZS treatment, indicating that the metal ions released by ZMS promote the activation of innate immunity via the cGAS‒STING pathway.[9] Significant variability in MDSCs and macrophages was observed only at the tumor site after ZS MN treatment. The gene discussed is STING1; the disease is neoplasm.