Although glycemic status in type 2 diabetes is controlled by different medications, T1D management is mostly confined to insulin therapy.8,9 There are several non-insulin medications including, thiazolidinedione, glucagon-like peptide-1 receptor agonists, dipeptidyl peptidase-4 inhibitor metformin, and sulfonylureas that have been assessed in clinical trials, however, they are not currently permitted to be used in patients with T1D.10 This evidence concerns the gene DPP4 and type 1 diabetes mellitus.