GRIN1 and movement disorder: N-methyl-D-aspartate receptor antibody encephalitis (NMDAR-Ab-E) is an autoimmune neurological disorder predominantly affecting women of reproductive age.1 2 Mediated by IgG autoantibodies against the NR1 (GluN1) subunit of the NMDA receptor (NMDAR-IgG), NMDAR-Ab-E presents with combinations of acute psychiatric disturbance, movement disorders, seizures, dysautonomia, hypoventilation and altered level of consciousness.