The findings of the research conducted by Effendi et al. [36] indicated that 73.5% of the E. coli bacteria present on broiler farms in Blitar, East Java, Indonesia, were pathogenic, as evidenced by the detection of the virulence genes iss and papC. These pathogenic bacteria can potentially cause a range of infections, including septicemia, urinary tract infections, and bacteremia. The gene discussed is PCDH8; the disease is bacterial infectious disease with sepsis.