PLOD1 and obesity due to melanocortin 4 receptor deficiency: Table 1 summarizes the key clinical data of the PCOS patients and healthy control enrolled in this study, including age group, catamenia, infertility, dermatological issues, obesity, and diabetic problems. The detailed information of all clinical presentations, including hormonal profile (luteinizing hormone, LH; follicle-stimulating hormone, FSH; anti-Mullerian hormone, AMH), as well as free testosterone levels is shown in Supplementary Table 1.