Our findings reveal that clusters #7 (VEGF mRNA), #11 (PTSD risk) and #12 (hla-g genotype) were more frequently cited before 2010, while clusters #2 (placental microRNA), #5 (non-coding RNA) and #6 (intrauterine growth restriction) gained prominence in the literature after 2010. The gene discussed is VEGFA; the disease is fetal growth restriction.