Research has shown that miR-144-3p and miR-146a-5p activate the Janus kinase (JAK)/transcription (STAT) signaling pathway (139) and promote dendritic cell activation and glycolysis (140) by targeting Caveolin-2 and autophagy-related 7 (ATG7), respectively, accelerating the occurrence of Sepsis-associated acute lung injury (SA-ALI). The gene discussed is SOAT1; the disease is acute respiratory distress syndrome.