Other researchers have noted that the absence of PSGL-1 in the low density lipoprotein receptor murine model (used to study hypocholesterolemia) significantly contributes to inhibition of the progression of atherosclerosis on the one hand, and also has been observed to regulate the metabolism of elements such as glucose, lipids, amino acids, and phospholipids (22) on the other hand. Here, SELPLG is linked to atherosclerosis.