Compared with the participants without severe AAC, individuals in the SAAC group exhibited advanced age, elevated NPS values, a higher prevalence of smoking, and were more prone to conditions such as hypertension, diabetes, hypercholesterolemia, arthritis, cancer, and osteoporosis, had lower BMI, hemoglobin, and platelets, and a higher value of urinary albumin to creatinine ratio, blood uric acid, red blood cell distribution width, glycosylated hemoglobin, vitamin D, and vitamin B12. Here, ALB is linked to arthritic joint disease.