CCL2 and colorectal carcinoma: For example, Fusobacterium nucleatum is more abundant in various tumors such as colorectal cancer(CRC), oral cancer, and gastric cancers and affects long-term prognosis (Mitsuhashi et al., 2015; Mima et al., 2016; Hsieh et al., 2022), A novel virulence protein of Fusobacterium nucleatum, Fn-Dps, has been found to promote invasion and metastasis of CRC cells by inducing EMT through upregulation of the chemokine CCL2/CCL7 (Mima et al., 2016).