On the other hand, AC is known for its anti-inflammatory properties [25], which are expected to inhibit the cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway to alleviate the immunosuppressive tumor environment [26], which is often exacerbated after PTT because of local inflammation-induced excessive expression of COX-2 and the accumulation of the downstream lipid metabolite PGE2 in the tumor [27,28]. This evidence concerns the gene PTGS2 and neoplasm.