designed a super‐deformable cationic liposome (UCL) for the transdermal delivery of IL‐4 plasmid in a psoriasis mouse model.[262] Histological examinations observed only mild epidermal hyperplasia, minimal reticular ridges on the ear surfaces, and a slight increase in tissue thickness in the dermal chambers after UCL/IL‐4 treatment. This evidence concerns the gene IL4 and psoriasis.