Then, the released TAAs would promote DCs antigen‐presentation and maturation, and thus boost T cells proliferation and infiltration.[14] Subsequently CD8+ T cells release IFN‐γ to inhibit neighboring tumor cells uptaking cystine for GSH synthesis, which further enhance the suppression of GPX4 and sensitize the cell to immunogenic ferroptosis inducing by Fe3+ and BSO. This evidence concerns the gene GPX4 and neoplasm.