PTK2 and acute promyelocytic leukemia: This study explores the relationship between lipid metabolism abnormalities in APL patients (such as changes in levels of TG, LDL-C, etc.)and their risk stratification, bleeding tendencies, and prognosis; validates the role of the PTK2 gene in the pathogenesis of APL and its regulatory function in lipid metabolism through gene expression and functional experiments; identifies lipid metabolism indicators and the PTK2 gene as potential biomarkers for risk stratification and prognosis assessment in APL, providing targets for future personalized therapy and new drug development.