IFNG and melanoma: This glycolipid has a modification in the galactose, with a hydrocinamoyl ester group on carbon 6, and also lacks the hydroxyl group on carbon 4 of the sphingosine, leading to an overall response polarized toward IFN-γ production by mouse and human iNKT cells, and showing strong anti-tumoral effect against B16-F10 melanoma (68).