BCL2L11 and Hepatic fibrosis: Down-regulation of several miRNAs (ssc-miR-363, ssc-miR-222, and ssc-miR-106a) targeting mRNAs coding for anti-apoptotic mitochondrial genes (BCL2L11 and BCL2L1) was also observed and suggests a reduction in cellular toxic insult and death corresponding to a reduction in hepatic fibrosis.