Bulk RNA‐seq of skin tissues revealed expression of several psoriasis‐related genes were substantially decreased in the BMS‐986165‐treated group, including proinflammatory cytokines (Il17a, Il17f, Il19, Il1b), chemokines (Cxcl2, Cxcl3, Ccl3, Ccl4), antimicrobial peptides (S100a8, S100a9, Defb14) and keratins (Krt6a, Krt6b, Krt16; Figures 1G and S1D).7, 10, 16. The gene discussed is S100A8; the disease is psoriasis.