We evaluated the expression of IGF1R and IR isoforms in a panel of four different cell lines: H295R and JIL-2266, derived from ACC primary tumours of female patients, MUC-1 and TVBF-7, derived from ACC distant and perirenal lymph-node metastasis of male patients, respectively. This evidence concerns the gene MUC1 and adrenal cortex carcinoma.