Moreover, the reduction of α-DIPA was negatively corelated with the increased levels of IL-17 and TNF-α, while was positively corelated with the decreased levels of chemokines such as IL-8 and IL-12 [49], which implying that the change of α-DIPA level might be a latent metabolic regulator influencing inflammatory responses and even MS course. Here, TNF is linked to myeloid sarcoma.