Moreover, the PKA regulator A-kinase anchor protein 12 (AKAP12), pleckstrin homology-like domain family A member 3 (PHLDA3), the transcriptional regulator RING1 and YY1-binding protein (RYBP), which has also been mentioned in connection with preeclampsia [33] and microtubule-associated serine/threonine protein kinase 4 (MAST4) were upregulated in both calcium conditions (Suppl. The gene discussed is AKAP12; the disease is preeclampsia.