Further syncytialization markers such as syncytin-1 GCM1, the steroid hormone synthesis enzyme 17-beta-hydroxysteroid dehydrogenase type 1 (HSD17B1) and the known preeclampsia marker inhibin alpha chain (INHA) as well as the calcium channel TRPV2 [20], the cadherin binding protein Cordon bleu protein like 1 (COBLL1) and Pleckstrin homology-like domain family B member 2 (PHLDB2) could not be clearly classified with regard to their calcium dependence (Suppl. This evidence concerns the gene COBLL1 and preeclampsia.