Based on the identification that LSP1 was negatively correlated with tumour purity, and positively correlated with the key immune infiltrates (Table 1), we used the TIMER2.0 and TISIDB databases to investigate the correlation between LSP1 expression and six main TILs (B cells, CD8+ T cells, CD4+ T cells, neutrophils, macrophages and dendritic cells) and immunomodulatory molecules including immunosuppressants, immunostimulants, MHC molecules and chemokines/receptors. The gene discussed is CD4; the disease is neoplasm.