MUC6 and colorectal carcinoma: MUC6-expressing MGN cells and MUC5AC-positive surface foveolar cells shared transcriptional similarities to MGN cells from healthy tissues and phenotypically resembled cells of the Brunner’s glands that are usually found in the duodenum only proximal to the sphincter of Oddi.2 In contrast, MUC6-expressing MGN cells accumulated also distal the sphincter of Oddi and in higher numbers in patients with celiac disease before the initiation of treatment as well as in CRC-affected tissues.