Although research on IL-2′s role in neurodegenerative diseases is limited, studies [70, 71] suggest it may offer therapeutic benefits in other neurodegenerative conditions like Alzheimer’s disease (AD), where IL-2 increased Treg cells in the brain, improved memory, restored spinal density, and reduced amyloid plaques [72]. The gene discussed is IL2; the disease is early-onset autosomal dominant Alzheimer disease.