APOA1 and Thrombocytopenia: In contrast to the clinical presentation, standard lipid parameters were similar including thrombocytopenia (due to hypersplenism), low low-density lipoprotein (LDL) levels (7-50 mg/dL), elevated triglycerides in all except patient #2 (targeted family testing in 19-year-old), and undetectable HDL and ApoA-I (Table 2).