We also observed that 11 protein–disease associations reached statistical significance only when the lead cis pQTL from the SomaScan platform was used but not when the lead cis pQTL from the Olink platform was used (CTSH, LGALS3, PARP1 and LILRB1 for AD; IDUA for PD; CD200, INHBC, THSD1 and AHSG for MS; and IDUA and INHBC for ALS; Supplementary Fig. 3). The gene discussed is THSD1; the disease is amyotrophic lateral sclerosis.