Fourteen protein–disease associations were statistically significant only in the Olink platform (ARHGAP45, EPHA1, GC, IDUA, TREML2 and PRSS8 for AD; SERPINE2 for PD; EGF, TPP1 and ATXN3 for ALS; and CTSH, IL7R, PARP1 and IDUA for MS). This evidence concerns the gene TREML2 and Alzheimer disease.