Eleven protein–disease pairs showed strong evidence of co-localization in both Olink and SomaScan platforms (C1R, C1S, CR1, GRN, PILRA, SIGLEC9, SIRPA for AD; and CR1, DKKL1, TNFRSF1A and WARS for MS). The gene discussed is SIGLEC9; the disease is Alzheimer disease.