Nine of the MS-associated proteins, six known (CD5, CD40, IL7R, STAT3, TNFRSF1A and TYMP) and three newly associated with MS (PARP1, PVALB and VEGFB), are involved in the pathogenesis of experimental autoimmune encephalomyelitis.105-113 This observation strengthens the validity of our findings. This evidence concerns the gene TNFRSF1A and experimental autoimmune encephalomyelitis.