In more recent year immunohistochemical studies can be used to distinguish the development stages of hemangiomas for example endothelial cells express CD31, von Willebrand factor, and urokinase in all phases while infantile hemangiomas express glucose transporter protein-1 (GLUT 1) during all phases of their development [12]. This evidence concerns the gene PECAM1 and capillary hemangioma.