Neurological diseases such as AD, ADHD, ALD, ANO, anxiety, ASD, BIP, epilepsy, learning and memory disorders, MDD, narcolepsy, SCZ, OCD, TOS, and brain aging have been extensively studied in the human brain, and significant proportions of genes have been proposed to be closely related to these diseases (Lu et al. 2004; Olah et al. 2018; Yang et al. 2022). This evidence concerns the gene HSPA5 and major depressive disorder.