The major pathological change in fibrotic cataracts is epithelial-mesenchymal transition (EMT).9 This process refers to the transformation of LECs from polygonal epithelial cells to spindle-shaped mesenchymal cells and is accompanied by enhanced migration and proliferation.1 Surgical injury and intraocular cytokine changes can induce the transdifferentiation of LECs into fibroblasts that express alpha-smooth muscle actin (α-SMA), vimentin, and secrete excessive fibronectin (FN) and collagen type I (Col I). Here, FN1 is linked to cataract.