We also noticed that in patients with AF, the level of almost the same above-mentioned apolipoproteins was abolished 24 h after cryoballoon ablation than in the individuals from Pre-CBA group (Apo-A1: −20.0%; Apo-A2: −17.3%; Apo-B: −14.4%; Apo-C1: −13.3%; Apo-C3: −12.6%; Apo-D: −22.2%; Apo-E: −14.3%; Apo-J: −21.5%; p < 0.05; Fig 1A,1B,1C,1D,1E,1F,1G, and 1I). This evidence concerns the gene APOE and atrial fibrillation.