Only the more infiltrative GL261 cohort displayed inter-subject associations between tumor cell proliferation (Ki67+ %) and metabolism, namely inverse correlations with tumor border/peritumoral glucose oxidation rate (Vglx: R=−0.91, p=0.030) and glucose-derived glutamate-glutamine elimination rate (kglx: R=−0.99, p<0.001). This evidence concerns the gene MKI67 and neoplasm.