In agreement with results from the mutants lacking the Las system, at an OD of 0.1, baicalein significantly blocked phage proliferation, with a more than fivefold difference observed at 2 h intervals between 2 and 12 h, rendering the cells resistant to phipa2 infection compared to the control group without baicalein (Fig. 4A and B, P < 0.0001). The gene discussed is LIAS; the disease is infection.