DLK1 and adrenal cortex carcinoma: RNA sequencing of the ACC cell line H295R, with DLK1 overexpression and knockdown, revealed that higher DLK1 expression was associated with lower expression of immune signaling gene set, suggesting that the carcinogenic role of DLK1 may, in part, be mediated through mechanisms associated with senescence‐induced immune remodeling [9] (Supplementary Figure S9A‐E).