TFAM and type 2 diabetes mellitus: Although the mitochondrial transcription factor A (TFAM) expression was increased only in Ow/Ob (Figure 3A,B), there were no differences in mitochondrial respiratory complex expression, except for succinate dehydrogenase (SDH) complex II (CII) in the mitochondrial electron transport chain (OXPHOS), which was elevated in Ow/Ob and T2D relative to HW (Figure 3A,C).