In addition, the SCLC cells expressing Notch1 protein (SBC-3, H69AR) demonstrated higher fold enrichment levels of acetylated histone H3 around the Notch1 promoter compared to the non-expressing Notch1 protein SCLC cells (H69, H1688) in the ChIP-qPCR assay (46). Here, NOTCH1 is linked to small cell lung carcinoma.