AKT1 and kidney disorder: While 736 decreased gene in ureteral stricture were related to kidney disease correlated biology process or pathway, such as PLA2G2F which highly expressed in damaged kidney and receptor of PLA2 demonstrated to be marker of nephropathy disease, as well as PPAR, Hippo and PI3K-Akt signaling pathway, which have been reported affect normal development of kidney and lead to renal disease.