DNAAF1 and primary ciliary dyskinesia: In segregation analysis of exome-wide sequencing data from 153 multicase TGCT families, we previously found evidence in two pedigrees of segregation with TGCTs for DNAAF1. The implication of DNAAF1, biallelic mutations that are reported to cause ciliary dyskinesia in humans, as a TGCT susceptibility gene was supported by data from functional studies and animal models [7].